SCHEMBL14749013

SCHEMBL14749013

CC(C)(C)C(=O)N1CCC(C2COC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.37
RIPK1 Q13546 4/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GPR119 Q8TDV5 3/20 0.35
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
CNR2 P34972 1/20 0.33
CXCR3 P49682 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18701700 0.88 DPP4 (0.40) DPP4RIPK1MEN1KMT2AGPR119
SCHEMBL24339766 0.82 RIPK1 (0.51) DPP4RIPK1MEN1KMT2AGPR119
SCHEMBL13888052 0.82 RIPK1 (0.46) DPP4RIPK1MEN1KMT2AALDH1A1
SCHEMBL24339741 0.82 EPHX2 (0.44) DPP4RIPK1MEN1KMT2ASMN1; SMN2
SCHEMBL20469332 0.79 DPP4 (0.40) DPP4RIPK1MEN1KMT2AALDH1A1
SCHEMBL24339765 0.79 GNAI3 (0.49) DPP4RIPK1MEN1KMT2A
SCHEMBL22657455 0.78 MEN1 (0.39) DPP4RIPK1MEN1KMT2AALDH1A1
SCHEMBL2674022 0.77 RECQL (0.59) GPR119RECQLSMN1; SMN2
SCHEMBL18701704 0.76 HSD11B1 (0.49) RIPK1ALDH1A1CNR2
SCHEMBL18701702 0.76 HSD11B1 (0.49) RIPK1ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 DPP4 1127/4885RIPK1 4241/4885MEN1 2565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.