SCHEMBL14749148

SCHEMBL14749148

C=Cc1ccc(-c2cccc(C(O)(C(F)(F)F)C(F)(F)F)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.42
PTPN5 P54829 3/20 0.41
NR1H3 Q13133 4/20 0.39
KIF11 P52732 1/20 0.38
SYK P43405 1/20 0.38
PTGS2 P35354 1/20 0.38
NR1H2 P55055 2/20 0.37
MAOB P27338 1/20 0.37
TRPM2 O94759 1/20 0.37
KDM1A O60341 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
SLC13A5 Q86YT5 1/20 0.35
HDAC2 Q92769 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14748502 0.85 PTPN5 (0.40) PTPN1PTPN5KIF11PTGS2MAOB
SCHEMBL12441428 0.83 NR1H3 (0.50) PTPN1PTPN5NR1H3KIF11SYK
SCHEMBL12441430 0.83 PTPN1 (0.48) PTPN1PTPN5NR1H3KIF11SYK
SCHEMBL4598751 0.82 TP53 (0.42) NR1H3NR1H2ALDH1A1
SCHEMBL643498 0.77 NR1H2 (0.56) NR1H3NR1H2ALDH1A1
SCHEMBL594542 0.75 ALDH1A1 (0.55) PTGS2HDAC2ALDH1A1
SCHEMBL13965655 0.73 NR1H3 (0.48) PTPN1PTPN5NR1H3KIF11SYK
SCHEMBL832913 0.73 NR1H3 (0.47) NR1H3NR1H2
SCHEMBL29870364 0.72 PTGS2 (0.56) PTGS2HDAC2ALDH1A1
SCHEMBL2095987 0.72 PTGS2 (0.56) PTGS2HDAC2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9052600-B2 Method for forming resist pattern and composition for forming protective film JSR CORPORATION (JP) 2015-06-09 US disclosed
US-20130059252-A1 METHOD FOR FORMING RESIST PATTERN AND COMPOSITION FOR FORMING PROTECTIVE FILM JSR CORPORATION (JP) 2013-03-07 US disclosed