SCHEMBL643498

SCHEMBL643498

C=Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 14/20 0.56
NR1H3 Q13133 14/20 0.56
ALDH1A1 P00352 1/20 0.48
MLYCD O95822 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131990 0.81 NR1H2 (0.68) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL3251427 0.79 ALDH1A1 (0.44) NR1H2NR1H3ALDH1A1
SCHEMBL1134055 0.79 ALDH1A1 (0.44) NR1H2NR1H3ALDH1A1
SCHEMBL5402087 0.79 HSD11B1 (0.46) NR1H2NR1H3ALDH1A1
SCHEMBL3278683 0.78 NR1H2 (0.50) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL847900 0.78 NR1H2 (0.43) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL17445916 0.78 ALDH1A1 (0.48) NR1H2NR1H3ALDH1A1
SCHEMBL6215692 0.78 NR1H2 (0.55) NR1H2NR1H3MLYCDSMN1; SMN2
Water SCHEMBL1684070 0.78 NR1H2 (0.65) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL14749148 0.77 PTPN1 (0.42) NR1H2NR1H3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 758 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565418-B Preparation method of 1,1,1,3,3, 3-hexafluoro-2- (4-vinyl phenyl) -2-propanol 河南工业大学 2020-02-14 CN claimed
CN-106565418-A Preparation method of 1,1,1,3,3-hexafluoro-2-(4-vinylphenyl)-2-propanol 河南工业大学 2017-04-19 CN claimed
US-20120120392-A1 Non-traditional agent/dusty agent detection system NORTHROP GRUMMAN SYSTEMS CORPORATION 2012-05-17 US claimed
US-6610456-B2 Such as 4-(hexafluorohydroxyisopropyl)styrene copolymer with tert-butyl alpha-trifluoromethyl acrylate; transparent to deep ultraviolet (DUV) radiation INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-08-26 US claimed
EP-0988517-A4 DETECTION OF CHEMICAL AGENT MATERIALS USING A SORBENT POLYMER AND FLUORESCENT PROBE CALSPAN CORP (US) 2003-03-19 EP claimed
US-20020192836-A1 Detection of chemical agent materials using a sorbent polymer and fluorescent probe CALSPAN SRL CORPORATION 2002-12-19 US claimed
US-20020164538-A1 Fluorine-containing styrene acrylate copolymers and use thereof in lithographic photoresist compositions INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-11-07 US claimed
EP-0988517-A2 DETECTION OF CHEMICAL AGENT MATERIALS USING A SORBENT POLYMER AND FLUORESCENT PROBE Calspan Corporation (US) 2000-03-29 EP claimed
US-6025036-A COATING A SUBSTRATE WITH A MATRIX, EXPOSURE TO LASER TO DESORB THE MATRIX THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2000-02-15 US claimed
WO-1999001737-A9 DETECTION OF CHEMICAL AGENT MATERIALS USING A SORBENT POLYMER AND FLUORESCENT PROBE CALSPAN CORP (US) 1999-05-20 WO claimed
WO-1999001737-A2 DETECTION OF CHEMICAL AGENT MATERIALS USING A SORBENT POLYMER AND FLUORESCENT PROBE CALSPAN CORPORATION (US) 1999-01-14 WO claimed
US-5250626-A Miscible blends of polyphosphazenes and acidic functional polymers EASTMAN KODAK COMPANY (US) 1993-10-05 US claimed
US-12460031-B2 Photosensitive resin composition, method for producing cured product of fluororesin, fluororesin, fluororesin film, bank and display element CENTRAL GLASS COMPANY, LIMITED (JP) 2025-11-04 US disclosed
US-12261298-B2 Polymer-inorganic solid-electrolyte interphase for stable metal batteries under lean electrolyte conditions THE PENN STATE RESEARCH FOUNDATION (US) 2025-03-25 US disclosed
CN-118973347-A Method for manufacturing patterned film substrate 中央硝子株式会社 2024-11-15 CN disclosed
CN-118945925-A Method for producing patterned film substrate, and fluorocopolymer 中央硝子株式会社 2024-11-12 CN disclosed
WO-1999001737-A9 DETECTION OF CHEMICAL AGENT MATERIALS USING A SORBENT POLYMER AND FLUORESCENT PROBE CALSPAN CORP (US) 1999-05-20 WO disclosed
EP-0916352-A2 Use of polymers to inhibit the denaturation of absorbed proteins HÜLS AKTIENGESELLSCHAFT (DE) 1999-05-19 EP disclosed
WO-1999001737-A2 DETECTION OF CHEMICAL AGENT MATERIALS USING A SORBENT POLYMER AND FLUORESCENT PROBE CALSPAN CORPORATION (US) 1999-01-14 WO disclosed
WO-1998053767-A1 METHOD OF PRODUCING A FILM COATING BY MATRIX ASSISTED PULSED LASER DEPOSITION THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1998-12-03 WO disclosed