Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.42 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749186 | 1.00 | GNAI3 (0.42) | GNAI3GNAO1GNAI1GLB1HTR1A | |
| SCHEMBL12912029 | 1.00 | GNAI3 (0.42) | GNAI3GNAO1GNAI1GLB1HTR1A | |
| SCHEMBL12911942 | 0.94 | GNAO1 (0.49) | GNAI3GNAO1GNAI1HTR1ADRD2 | |
| SCHEMBL24261571 | 0.93 | GNAO1 (0.51) | GNAI3GNAO1GNAI1HTR1ADRD2 | |
| SCHEMBL26511527 | 0.93 | GNAO1 (0.51) | GNAI3GNAO1GNAI1HTR1ADRD2 | |
| SCHEMBL12911893 | 0.89 | BCHE (0.45) | — | |
| SCHEMBL15133969 | 0.88 | DRD2 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12064339 | 0.88 | GNAO1 (0.48) | GNAI3GNAO1GNAI1GLB1 | |
| SCHEMBL15685442 | 0.88 | DRD2 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL10152381 | 0.88 | DRD2 (0.41) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029479-A1 | MYCOPHENOLIC ACID DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 中国科学院上海药物研究所 (CN) | 2013-03-07 | — | — | WO | disclosed |
| WO-2011152485-A1 | NOVEL 4,5-FUSED PYRIMIDINE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2011-12-08 | — | — | WO | disclosed |