SCHEMBL14749525

SCHEMBL14749525

CCc1ccc2cc(-c3ccc(C)cc3)c(=O)oc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.66
MAOB P27338 8/20 0.60
ADORA3 P0DMS8 3/20 0.60
PON1 P27169 1/20 0.59
ACHE P22303 2/20 0.56
MAOA P21397 1/20 0.55
ESR2 Q92731 1/20 0.52
GLA P06280 3/20 0.51
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 1/20 0.48
MEN1 O00255 2/20 0.48
RAB9A P51151 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
SIRT3 Q9NTG7 1/20 0.48
ERAP1 Q9NZ08 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL802632 0.93 ESR2 (0.56) MIFMAOBADORA3PON1ACHE
SCHEMBL12386448 0.87 MIF (0.64) MIFMAOBADORA3PON1ACHE
SCHEMBL21761558 0.86 MIF (0.56) MIFMAOBADORA3PON1ACHE
SCHEMBL10024076 0.85 MIF (0.77) MIFMAOBADORA3PON1MAOA
SCHEMBL12386450 0.84 ESR2 (0.51) MIFACHEESR2GLATDP1
SCHEMBL9237422 0.84 MIF (0.67) MIFACHEESR2GLATDP1
SCHEMBL13487216 0.84 PGR (0.56) MIFPON1ESR2GLATDP1
SCHEMBL23316808 0.82 ESR2 (0.76) MIFMAOBMAOAESR2GLA
SCHEMBL12386449 0.82 MIF (0.60) MIFMAOBADORA3PON1ACHE
SCHEMBL21761395 0.81 MIF (0.53) MIFMAOBADORA3PON1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180223189-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-08-09 US disclosed
US-20180155625-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2018-06-07 US disclosed
US-9938464-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2018-04-10 US disclosed
US-9862887-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2018-01-09 US disclosed
US-20180002603-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2018-01-04 US disclosed
US-20170349827-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-12-07 US disclosed
US-20170349832-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-12-07 US disclosed
US-9822305-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2017-11-21 US disclosed
US-20170306230-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-10-26 US disclosed
US-20170253801-A1 LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2017-09-07 US disclosed
US-20150301344-A1 LENS ELEMENT MERCK PATENT GMBH (DE) 2015-10-22 US disclosed
US-20150247089-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-09-03 US disclosed
US-9120969-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2015-09-01 US disclosed
US-20150129800-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-05-14 US disclosed
US-20140225035-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2014-08-14 US disclosed
US-20140158934-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2014-06-12 US disclosed
US-20140125938-A1 POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2014-05-08 US disclosed
US-20140077130-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2014-03-20 US disclosed
US-8659737-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2014-02-25 US disclosed
US-20130057947-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140125938-A1 POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS LPXN, BPHL, MAP1LC3C MIF 1495/4885MAOB 1838/4885ADORA3 4836/4885
US-20150129800-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY CCND2, CFD, CRY1 MIF 108/4885MAOB 1186/4885ADORA3 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.