Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RGS4 | P49798 | 1/20 | 0.32 |
| ▸ | RGS8 | P57771 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749797 | 0.81 | ATM (0.36) | POLBPIK3CDKMT2AL3MBTL1MAPT | |
| SCHEMBL14749802 | 0.77 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1RGS4RGS8ATM | |
| SCHEMBL10748338 | 0.77 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1RGS4RGS8ATM | |
| SCHEMBL14749798 | 0.77 | PIK3CD (0.37) | PIK3CDKMT2AL3MBTL1MAPTATM | |
| SCHEMBL14749805 | 0.71 | AR (0.39) | POLBPIK3CDKMT2AMAPTMEN1 | |
| SCHEMBL14749795 | 0.71 | TSHR (0.37) | PIK3CDKMT2AL3MBTL1MAPTATM | |
| SCHEMBL14827918 | 0.71 | SLC5A1 (0.37) | ALDH1A1RGS4RGS8ATMHPGD | |
| SCHEMBL16181414 | 0.70 | PIK3C3 (0.37) | PIK3CDKMT2AMAPT | |
| SCHEMBL1438921 | 0.70 | CMA1 (0.46) | ALDH1A1KMT2AL3MBTL1MAPTKDM4E | |
| SCHEMBL11283658 | 0.69 | SMN1; SMN2 (0.45) | KMT2AATMSMN1; SMN2KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524599-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2019-08-14 | — | — | EP | disclosed |
| WO-2013031922-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2013-03-07 | — | — | WO | disclosed |