Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749798 | 0.85 | PIK3CD (0.37) | ATMPIK3CDNPSR1MAPTKMT2A | |
| SCHEMBL14749787 | 0.81 | ALDH1A1 (0.36) | ATMPIK3CDNPSR1MAPTKMT2A | |
| SCHEMBL14749805 | 0.75 | AR (0.39) | PIK3CDMAPTKMT2APOLBMEN1 | |
| SCHEMBL14749795 | 0.75 | TSHR (0.37) | ATMPIK3CDMAPTKMT2AMEN1 | |
| SCHEMBL9803351 | 0.75 | PER2 (0.37) | POLBL3MBTL1 | |
| SCHEMBL14749807 | 0.75 | PER2 (0.37) | POLBL3MBTL1 | |
| SCHEMBL16181414 | 0.74 | PIK3C3 (0.37) | PIK3CDMAPTKMT2APIK3C3 | |
| SCHEMBL3514840 | 0.72 | MEN1 (0.36) | KMT2AMEN1 | |
| SCHEMBL13693984 | 0.69 | MERTK (0.33) | MAPTKMT2AMEN1 | |
| SCHEMBL24983622 | 0.69 | PIK3CD (0.67) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013031922-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2013-03-07 | — | — | WO | disclosed |