SCHEMBL1475142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1474926	0.92	SIGMAR1 (0.42)	ACKR3ALDH1A1KDM4EPOLBTSHR
	SCHEMBL12827755	0.87	KDM4E (0.37)	ACKR3ALDH1A1KDM4EPOLBTSHR
	SCHEMBL1474799	0.87	KDM4E (0.47)	ALDH1A1KDM4ESIGMAR1TDP1CHRM1
	SCHEMBL1475172	0.84	ACKR3 (0.37)	ACKR3ALDH1A1KDM4ESIGMAR1JAK2
	SCHEMBL1475069	0.84	SIGMAR1 (0.43)	ALDH1A1KDM4EPOLBSIGMAR1
	SCHEMBL1475789	0.80	SIGMAR1 (0.46)	ACKR3ALDH1A1KDM4EPOLBSIGMAR1
	SCHEMBL1475330	0.80	KDM4E (0.40)	P2RX7ACKR3ALDH1A1KDM4EPOLB
	SCHEMBL1475174	0.79	HTR2A (0.42)	KDM4ESIGMAR1
	SCHEMBL1477399	0.79	ABL1 (0.45)	ACKR3TSHRSIGMAR1
	SCHEMBL1475662	0.78	ALDH1A1 (0.41)	TAAR1ALDH1A1KDM4EPOLBSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.