Ceftezole

Ceftezole

SCHEMBL147529

O=C(Cn1cnnn1)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CS[C@H]12

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.79
SLC22A6 Q4U2R8 2/20 0.79
SLC22A8 Q8TCC7 2/20 0.79
SLC22A11 Q9NSA0 2/20 0.79
PTGS2 P35354 1/20 0.79
MAPT P10636 9/20 0.67
TDP1 Q9NUW8 9/20 0.67
HSD17B10 Q99714 2/20 0.67
ABCC4 O15439 1/20 0.67
BLM P54132 1/20 0.67
CYP3A4 P08684 1/20 0.67
NFKB1 P19838 1/20 0.67
POLB P06746 10/20 0.57
PTGS1 P23219 1/20 0.56
PDE4A P27815 1/20 0.56
KDR P35968 1/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ceftezole SCHEMBL11033793 1.00 LMNA (0.79) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL11033790 1.00 LMNA (0.79) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL2259026 0.99 LMNA (0.78) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL1649887 0.92 TDP1 (0.79) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL3424683 0.88 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL16072809 0.88 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL11031717 0.88 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL3894722 0.88 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL2842 0.88 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL4930576 0.88 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4659 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637481-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2026-05-26 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof RECREO PHARMACEUTICALS LLC (US) 2025-07-29 US claimed
US-20250222118-A1 Beta-Lactam-Cannabinoid Conjugate Molecules DIVERSE BIOTECH INC (US) 2025-07-10 US claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
US-5637579-A BETA-LACTAMASE INHIBITORS; BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1997-06-10 US claimed
EP-0563387-B1 CEPHALOSPORINASE TESTING AGENT SHOWA PHARM CHEM IND (JP) 1997-04-23 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0678095-A1 CRYSTALLINE PENICILLIN DERIVATIVE, AND ITS PRODUCTION AND USE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1995-10-25 EP claimed
WO-1995012601-A1 CRYSTALLINE PENICILLIN DERIVATIVE, AND ITS PRODUCTION AND USE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1995-05-11 WO claimed
US-5350680-A Determining if infection causing bacteria are beta-lactamase producers SHOWA YAKUHIN KAKO CO., LTD. (JP) 1994-09-27 US claimed
US-4414204-A WITH A MURAMYL-PEPTIDE CIBA-GEIGY CORPORATION (US) 1983-11-08 US claimed