SCHEMBL1475449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12827750	0.90	CCR8 (0.35)	CYP3A4CYP2D6CCR8KCNH2EGLN1
	SCHEMBL1476247	0.89	MCHR1 (0.37)	DPP4MCHR1POLBALDH1A1KDM4E
	SCHEMBL1475438	0.88	EGLN1 (0.41)	POLBALDH1A1KDM4EPARP1SIGMAR1
	SCHEMBL1475069	0.80	SIGMAR1 (0.43)	POLBALDH1A1KDM4ESIGMAR1KMT2A
	SCHEMBL1475313	0.80	MCHR1 (0.39)	MCHR1POLBALDH1A1KDM4ESIGMAR1
	SCHEMBL12827517	0.79	CCR8 (0.33)	CCR8KCNH2EGLN1
	SCHEMBL1475574	0.79	KDM4E (0.37)	DPP4POLBALDH1A1KDM4EPARP1
	SCHEMBL1475865	0.78	SIGMAR1 (0.42)	POLBSIGMAR1MEN1KMT2A
	SCHEMBL12827753	0.77	ALDH1A1 (0.48)	ALDH1A1PARP1MEN1KMT2ATNKS
	SCHEMBL1475654	0.77	EGLN1 (0.41)	POLBALDH1A1KDM4ESIGMAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.