Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872358 | 0.86 | TSHR (0.48) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL871423 | 0.79 | TSHR (0.41) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11448991 | 0.79 | TSHR (0.41) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18555483 | 0.79 | TSHR (0.44) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23668796 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TSHRHPGDALOX15ALOX12 | |
| SCHEMBL27876875 | 0.76 | PSMB5 (0.41) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11281953 | 0.76 | ATM (0.40) | ALDH1A1TSHRHPGDSLC1A3SLC1A2 | |
| SCHEMBL9188228 | 0.75 | IDO1 (0.36) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL3778472 | 0.75 | TSHR (0.44) | ALDH1A1TSHRHPGDALOX15ALOX12 | |
| SCHEMBL7011964 | 0.74 | TSHR (0.48) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | KIT, PDGFRA, PDGFRB | ALDH1A1 1538/4885TSHR 4686/4885HPGD 3740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.