Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819314 | 0.84 | TSHR (0.41) | TSHRALDH1A1IDO1SLC1A3SLC1A2 | |
| SCHEMBL10747585 | 0.79 | TSHR (0.44) | TSHRALDH1A1IDO1SLC1A3SLC1A2 | |
| SCHEMBL6800327 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL7526436 | 0.76 | CHRNB2 (0.51) | TSHRALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL23668796 | 0.75 | ALDH1A1 (0.40) | TSHRALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL3778470 | 0.75 | TSHR (0.56) | TSHRALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL14754591 | 0.75 | ALDH1A1 (0.40) | TSHRALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL5812823 | 0.74 | TSHR (0.48) | TSHRALDH1A1HPGDIDO1SLC1A3 | |
| SCHEMBL15039477 | 0.74 | TSHR (0.48) | TSHRALDH1A1HPGDIDO1SLC1A3 | |
| SCHEMBL2644673 | 0.74 | TSHR (0.48) | TSHRALDH1A1IDO1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323000-A1 | METHOD AND PROCESS FOR PREPARING CARDIOLIPIN | NEOPHARM, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| EP-1986607-A2 | METHOD AND PROCESS FOR PREPARING CARDIOLIPIN | Neopharm, Inc. (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007100808-A2 | METHOD AND PROCESS FOR PREPARING CARDIOLIPIN | NEOPHARM, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20050266068-A1 | Cardiolipin molecules and methods of synthesis | NEOPHARM, INC. (US) | 2005-12-01 | — | — | US | disclosed |
| US-20050181037-A1 | Cardiolipin compositions their methods of preparation and use | NEOPHARM, INC. (US) | 2005-08-18 | — | — | US | disclosed |
| EP-1556392-A1 | CARDIOLIPIN MOLECULES AND METHOD OF SYNTHESIS | Neopharm, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004062569-A2 | CARDIOLIPIN COMPOSITIONS THEIR METHODS OF PREPARATION AND USE | NEOPHARM, INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| WO-2004039817-A9 | CARDIOLIPIN MOLECULES AND METHOD OF SYNTHESIS | NEOPHARM INC (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004039817-A1 | CARDIOLIPIN MOLECULES AND METHOD OF SYNTHESIS | NEOPHARM, INC. (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050266068-A1 | Cardiolipin molecules and methods of synthesis | PHOSPHO1, MGLL, LIPA | TSHR 3675/4885ALDH1A1 4029/4885HPGD 1833/4885 |
| US-20050181037-A1 | Cardiolipin compositions their methods of preparation and use | LIPA, LCLAT1, PHOSPHO1 | TSHR 4032/4885ALDH1A1 3662/4885HPGD 1101/4885 |
| US-20100323000-A1 | METHOD AND PROCESS FOR PREPARING CARDIOLIPIN | PHOSPHO1, SGMS1, SGMS2 | TSHR 2133/4885ALDH1A1 4113/4885HPGD 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.