Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 6/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15295521 | 0.83 | MCL1 (0.70) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6559997 | 0.82 | GAA (0.71) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL15984890 | 0.82 | KDM4E (0.64) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL14756049 | 0.81 | GAA (0.70) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL15082524 | 0.81 | GAA (0.62) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL31454860 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL17615425 | 0.78 | ERN1 (0.66) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6560136 | 0.76 | KDM4E (0.64) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL16710500 | 0.75 | GAA (0.69) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL18074001 | 0.73 | KDM4E (0.62) | ALDH1A1KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081284-A1 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |