SCHEMBL1475643

SCHEMBL1475643

CC(C)(C)OC(=O)N1CCC2(CC1)CC(OS(C)(=O)=O)C2

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 12/20 0.51
EPHX2 P34913 1/20 0.42
USP2 O75604 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NAMPT P43490 3/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9994892 0.92 GPR119 (0.44) GPR119
SCHEMBL485093 0.88 GPR119 (0.53) GPR119USP2SMN1; SMN2HPGD
SCHEMBL14661920 0.86 EPHX2 (0.38) GPR119EPHX2USP2SMN1; SMN2HPGD
SCHEMBL14662698 0.84 HPGD (0.39) GPR119EPHX2USP2SMN1; SMN2NAMPT
SCHEMBL31565546 0.83 GPR119 (0.46) GPR119
SCHEMBL25234342 0.82 GPR119 (0.49) GPR119EPHX2USP2SMN1; SMN2NAMPT
SCHEMBL1474868 0.82 USP2 (0.49) GPR119EPHX2USP2SMN1; SMN2NAMPT
SCHEMBL21384373 0.81 GPR119 (0.40) GPR119EPHX2HPGD
SCHEMBL21401557 0.81 GPR119 (0.40) GPR119EPHX2HPGD
SCHEMBL30845965 0.81 GPR119 (0.40) GPR119EPHX2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079983-A FGFR3 inhibitor compounds 2026-05-26 CN disclosed
CN-122079985-A FGFR3 inhibitor compounds 2026-05-26 CN disclosed
CN-122079984-A FGFR3 inhibitor compounds 2026-05-26 CN disclosed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-12606533-B2 3-phenylpropylamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
EP-4514794-B1 FGFR2 INHIBITOR COMPOUNDS LILLY CO ELI (US) 2026-03-25 EP disclosed
US-12558428-B2 Heterobifunctional compounds and their use in treating disease HALDA THERAPEUTICS OPCO, INC. (US) 2026-02-24 US disclosed
US-20260042749-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2026-02-12 US disclosed
US-12545659-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-02-10 US disclosed
US-12539295-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-02-03 US disclosed
US-20070293496-A1 Nitrogen containing heterocyclic compounds and medicines containing the same OZAKI FUMIHIRO 2007-12-20 US disclosed
US-7265108-B2 Nitrogen containing heterocyclic compounds and medicines containing the same EISAI CO., LTD. (JP) 2007-09-04 US disclosed
US-7265108-B2 Nitrogen containing heterocyclic compounds and medicines containing the same EISAI CO., LTD. (JP) 2007-09-04 US disclosed
US-7265108-B2 Nitrogen containing heterocyclic compounds and medicines containing the same EISAI CO., LTD. (JP) 2007-09-04 US disclosed
EP-1484327-B1 NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF EISAI R&D MAN CO LTD (JP) 2007-08-01 EP disclosed
EP-1484327-B1 NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF EISAI R&D MAN CO LTD (JP) 2007-08-01 EP disclosed
US-6995144-B2 Nitrogen containing heterocyclic compounds and medicines containing the same EISAI CO., LTD. (JP) 2006-02-07 US disclosed
US-20050245527-A1 Nitrogen containing heterocyclic compounds and medicines containing the same EISAI R&D MANAGEMENT CO., LTD. (JP) 2005-11-03 US disclosed
EP-1484327-A1 NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF Eisai Co., Ltd. (JP) 2004-12-08 EP disclosed
US-20040167224-A1 Nitrogen containing heterocyclic compounds and medicines containing the same EISAI R&D MANAGEMENT CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293496-A1 Nitrogen containing heterocyclic compounds and medicines containing the same XDH, NQO1, CYP1A1 GPR119 2649/4885EPHX2 1557/4885USP2 3639/4885
US-12545659-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK4 GPR119 1443/4885EPHX2 3556/4885USP2 740/4885
US-12539295-B2 IRAK degraders and uses thereof IRAK2, IRAK4, IRAK3 GPR119 812/4885EPHX2 1576/4885USP2 551/4885
US-12558428-B2 Heterobifunctional compounds and their use in treating disease BRCA1, H1-0, FOXM1 GPR119 2252/4885EPHX2 1242/4885USP2 4440/4885
US-20260042749-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK4 GPR119 932/4885EPHX2 1830/4885USP2 684/4885
US-12606533-B2 3-phenylpropylamine derivative SF3A1, SF1, HTR1D GPR119 467/4885EPHX2 2146/4885USP2 1847/4885
US-20040167224-A1 Nitrogen containing heterocyclic compounds and medicines containing the same NQO1, CBR1, NOX1 GPR119 1520/4885EPHX2 2349/4885USP2 3522/4885
US-20050245527-A1 Nitrogen containing heterocyclic compounds and medicines containing the same XDH, NQO1, CYP1A1 GPR119 2649/4885EPHX2 1557/4885USP2 3639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.