Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12669969 | 0.86 | KDM4E (0.37) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL870522 | 0.79 | NPC1 (0.50) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL9598573 | 0.78 | PIK3CG (0.55) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL9598420 | 0.78 | KDM4E (0.63) | KDM4ETP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL871183 | 0.78 | GRM5 (0.47) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL973963 | 0.78 | DRD2 (0.43) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL9597339 | 0.73 | MCHR1 (0.50) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL21355035 | 0.73 | METTL3 (0.47) | MCHR1 | |
| SCHEMBL19292088 | 0.73 | MCHR1 (0.39) | MCHR1KDM4ETP53RAB9ANPC1 | |
| SCHEMBL102061 | 0.72 | KDM4E (0.56) | KDM4ETP53RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |