SCHEMBL871183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22529082	0.81	GRM5 (0.47)	GRM5METTL3APPCYP11B1CYP11B2
	SCHEMBL103426	0.81	GRM5 (0.47)	GRM5METTL3APPCYP11B1CYP11B2
	SCHEMBL8180039	0.81	GRM5 (0.47)	GRM5METTL3APPCYP11B1CYP11B2
	SCHEMBL870522	0.79	NPC1 (0.50)	MCHR1METTL3APPTP53ALDH1A1
	Hydrochloric Acid SCHEMBL27146172	0.78	ALDH1A1 (0.55)	GRM5METTL3APPTP53ALDH1A1
	SCHEMBL14758258	0.78	MCHR1 (0.42)	MCHR1TP53ALDH1A1NPC1RAB9A
	SCHEMBL9598420	0.78	KDM4E (0.63)	TP53ALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL973963	0.78	DRD2 (0.43)	MCHR1APPTP53ALDH1A1NPC1
	SCHEMBL9598573	0.78	PIK3CG (0.55)	MCHR1METTL3APPTP53ALDH1A1
	SCHEMBL103410	0.75	GRM5 (0.57)	GRM5METTL3APPCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.