Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 11/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26087484 | 0.82 | F3 (0.48) | F3F2F10PRSS1PRSS2 | |
| SCHEMBL26089278 | 0.80 | KDM4E (0.68) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7713633 | 0.77 | RIPK1 (0.58) | GSK3B | |
| SCHEMBL26088530 | 0.75 | LOXL2 (0.47) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL22128259 | 0.75 | KDM4E (0.43) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL29871364 | 0.75 | F3 (0.48) | F3F2TRPA1CYP19A1F10 | |
| SCHEMBL3837963 | 0.75 | F3 (0.48) | F3F2TRPA1CYP19A1F10 | |
| SCHEMBL26086870 | 0.74 | F3 (0.47) | KMT2AF3F2F10PRSS1 | |
| SCHEMBL26088542 | 0.71 | DAO (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2F3 | |
| SCHEMBL28317738 | 0.71 | TRPA1 (0.50) | F3F2TRPA1CYP19A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566481-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | Merck Sharp & Dohme Corp. (US) | 2013-03-13 | — | — | EP | disclosed |