Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515942 | 0.72 | SMYD3 (0.36) | MTNR1ASMYD3MASP2F2PTK2B | |
| SCHEMBL515941 | 0.72 | SMYD3 (0.36) | MTNR1ASMYD3MASP2F2PTK2B | |
| SCHEMBL516119 | 0.67 | OPRM1 (0.35) | MTNR1ASMYD3PTK2B | |
| SCHEMBL515959 | 0.67 | OPRM1 (0.35) | SMYD3 | |
| SCHEMBL515960 | 0.67 | OPRM1 (0.35) | SMYD3 | |
| SCHEMBL516721 | 0.67 | HTR1A (0.35) | MTNR1ASMYD3MASP2F2PTK2B | |
| SCHEMBL516720 | 0.67 | HTR1A (0.35) | MTNR1ASMYD3MASP2F2PTK2B | |
| SCHEMBL516120 | 0.67 | OPRM1 (0.35) | MTNR1ASMYD3PTK2B | |
| SCHEMBL515725 | 0.65 | RIPK1 (0.35) | SMYD3PTK2B | |
| SCHEMBL1268909 | 0.62 | SMYD3 (0.59) | MTNR1ASMYD3MASP2F2PTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414323-B1 | DERIVATIVES OF AMINOCYCLOBUTANE OR AMINOCYCLOBUTENE, THEIR METHOD OF PREPARATION AND THEIR USE AS MEDICAL PRODUCTS | PF MEDICAMENT (FR) | 2013-03-13 | — | — | EP | claimed |