Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569635 | 0.76 | BCHE (0.43) | ALDH1A1KMT2ABCHEHSD17B10LMNA | |
| SCHEMBL28985430 | 0.72 | BCHE (0.41) | ALDH1A1KMT2ABCHEHSD17B10LMNA | |
| SCHEMBL16356254 | 0.72 | BCHE (0.41) | ALDH1A1KMT2ABCHEHSD17B10MEN1 | |
| SCHEMBL5570690 | 0.72 | KMT2A (0.39) | ALDH1A1KMT2AL3MBTL1BCHEMEN1 | |
| SCHEMBL74973 | 0.72 | L3MBTL1 (0.55) | ALDH1A1KMT2AL3MBTL1BCHEHSD17B10 | |
| SCHEMBL31241181 | 0.72 | L3MBTL1 (0.55) | ALDH1A1KMT2AL3MBTL1BCHEHSD17B10 | |
| SCHEMBL5573133 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KMT2ABCHEHSD17B10MEN1 | |
| SCHEMBL4427684 | 0.68 | HSD17B10 (0.55) | ALDH1A1KMT2AL3MBTL1BCHEHSD17B10 | |
| Ethylene Glycol SCHEMBL8989789 | 0.68 | L3MBTL1 (0.51) | ALDH1A1KMT2AL3MBTL1BCHEHSD17B10 | |
| SCHEMBL11424950 | 0.67 | BCHE (0.40) | ALDH1A1KMT2ABCHEMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806400-B1 | Inactivation method | FERMENTAS UAB (LT) | 2013-03-13 | — | — | EP | disclosed |