SCHEMBL16356254

SCHEMBL16356254

CCOC(=O)N1C(=O)c2c(C)sc(C)c2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.41
FHIT P49789 1/20 0.37
ALDH1A1 P00352 9/20 0.36
HPGD P15428 7/20 0.36
MAPT P10636 6/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
LMNA P02545 2/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36
CCR6 P51684 1/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 4/20 0.35
HSD17B10 Q99714 4/20 0.35
APP P05067 1/20 0.35
SNCA P37840 1/20 0.35
GSK3A P49840 2/20 0.34
GSK3B P49841 2/20 0.34
PIN1 Q13526 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16366801 0.79 BCHE (0.37) BCHEALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL5569635 0.77 BCHE (0.43) BCHEALDH1A1MAPTLMNAPKM
SCHEMBL28985430 0.74 BCHE (0.41) BCHEALDH1A1LMNAGAAHSD17B10
SCHEMBL14760440 0.72 ALDH1A1 (0.41) BCHEALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL31241181 0.69 L3MBTL1 (0.55) BCHEALDH1A1MAPTHTTGAA
SCHEMBL74973 0.69 L3MBTL1 (0.55) BCHEALDH1A1MAPTHTTGAA
SCHEMBL5570690 0.69 KMT2A (0.39) BCHEALDH1A1MAPTNPSR1LMNA
SCHEMBL23121513 0.68 ANPEP (0.44) BCHEALDH1A1MAPTLMNAHTT
SCHEMBL537408 0.68 KDM4E (0.56) ALDH1A1HPGDMAPTSMN1; SMN2LMNA
SCHEMBL30225703 0.68 KDM4E (0.56) ALDH1A1HPGDMAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9412950-B2 Polymer compound and organic photoelectric conversion device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140373912-A1 POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-25 US disclosed