Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13597619 | 1.00 | LMNA (0.44) | LMNATSHRTK1ALBPKM | |
| SCHEMBL14760442 | 1.00 | LMNA (0.44) | LMNATSHRTK1ALBPKM | |
| SCHEMBL20748395 | 1.00 | LMNA (0.44) | LMNATSHRTK1ALBPKM | |
| SCHEMBL20748394 | 0.89 | TOP2A (0.40) | TK1 | |
| SCHEMBL17117062 | 0.88 | LMNA (0.33) | LMNATSHRTK1ALBPKM | |
| SCHEMBL15061820 | 0.87 | RNASE1 (0.44) | LMNATK1 | |
| SCHEMBL21538043 | 0.86 | LMNA (0.49) | LMNATSHRTK1ALBPKM | |
| SCHEMBL23734302 | 0.86 | LMNA (0.37) | LMNATSHRTK1ALBPKM | |
| SCHEMBL20810838 | 0.86 | RNASE1 (0.43) | LMNATK1 | |
| SCHEMBL20810870 | 0.86 | RNASE1 (0.43) | LMNATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530578-B1 | MODIFIED NUCLEOTIDES FOR POLYNUCLEOTIDE SEQUENCING | ILLUMINA CAMBRIDGE LTD (GB) | 2013-03-13 | — | — | EP | disclosed |