SCHEMBL14760485

SCHEMBL14760485

CCOC(=O)C(F)(F)OC12CC3CC(C1)CC(C(=O)OCCC(F)(F)C(F)(F)S(=O)(=O)O)(C3)C2.[NaH]

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.37
EPHX2 P34913 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14770319 0.99 NPSR1 (0.38) NPSR1EPHX2MEN1KMT2AL3MBTL1
SCHEMBL14760484 0.90 NPSR1 (0.36) NPSR1EPHX2MEN1KMT2AL3MBTL1
SCHEMBL14760564 0.88 NPSR1 (0.37) NPSR1
SCHEMBL14770349 0.87 NPSR1 (0.38) NPSR1MEN1KMT2AL3MBTL1
SCHEMBL24268504 0.86 NPSR1 (0.41) NPSR1MEN1KMT2AL3MBTL1
SCHEMBL14770325 0.84 LMNA (0.35) NPSR1EPHX2MEN1KMT2AL3MBTL1
SCHEMBL12333914 0.84 NPSR1 (0.44) NPSR1EPHX2MEN1KMT2AL3MBTL1
SCHEMBL14760465 0.83 NPSR1 (0.38) NPSR1MEN1KMT2AL3MBTL1
SCHEMBL14760515 0.82 EPHX2 (0.34) NPSR1EPHX2MEN1KMT2AL3MBTL1
SCHEMBL14760516 0.82 NPSR1 (0.40) NPSR1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244185-A9 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT JSR CORPORATION (JP) 2013-09-19 US disclosed
US-20130065186-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT JSR CORPORATION (JP) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130244185-A9 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT GLRA3, RER1, RXRG NPSR1 1899/4885EPHX2 195/4885MEN1 3808/4885
US-20130065186-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT GLRA3, RER1, FPR3 NPSR1 1960/4885EPHX2 171/4885MEN1 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.