SCHEMBL14760909

SCHEMBL14760909

CC(C)(C)c1cc(O)c(C(=O)O)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.52
GLRB P48167 1/20 0.52
CYP3A4 P08684 3/20 0.47
ACHE P22303 1/20 0.47
HPGD P15428 2/20 0.46
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
RXRB P28702 6/20 0.46
RXRA P19793 5/20 0.46
RXRG P48443 2/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16147679 0.88 GLRA3 (0.55) GLRA3GLRBCYP3A4ACHEHPGD
SCHEMBL15459988 0.86 GLRA3 (0.44) GLRA3GLRBCYP3A4ACHEHPGD
SCHEMBL22166937 0.84 GLRA3 (0.40) GLRA3GLRBCYP3A4ACHEHPGD
SCHEMBL9857887 0.83 FABP3 (0.50) GLRA3GLRBCYP3A4ACHEHPGD
SCHEMBL501930 0.79 RXRB (0.50) GLRA3GLRBCYP3A4ACHEALDH1A1
SCHEMBL31013931 0.77 CES2 (0.46) CYP3A4ACHEHPGDALDH1A1HSD17B10
SCHEMBL6466602 0.77 GLRA3 (0.57) GLRA3GLRBCYP3A4ALDH1A1ALOX15
SCHEMBL11756982 0.77 AKR1C2 (0.49) GLRA3GLRBHPGDALDH1A1ALOX15
SCHEMBL13763260 0.76 GLRA3 (0.45) GLRA3GLRBCYP3A4ALOX15HSD17B10
SCHEMBL28760467 0.76 GLRA3 (0.45) GLRA3GLRBCYP3A4ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739223-B2 Surface primer compositions and methods of use ENVISTA (US) 2023-08-29 US disclosed
US-11739223-B2 Surface primer compositions and methods of use ENVISTA (US) 2023-08-29 US disclosed
US-20230112086-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2023-04-13 US disclosed
US-11453790-B2 Photo-cleavable primer compositions and methods of use ENVISTA (US) 2022-09-27 US disclosed
US-11352512-B2 Surface primer compositions and methods of use ENVISTA (US) 2022-06-07 US disclosed
US-11214715-B2 Ionic polymers and their use as wet-adhesives and coatings ACatechol, Inc. (US) 2022-01-04 US disclosed
US-20200347247-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ENVISTA (US) 2020-11-05 US disclosed
US-20200347248-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ENVISTA (US) 2020-11-05 US disclosed
US-10696698-B2 Surface primer compositions and methods of use ORMCO CORPORATION 2020-06-30 US disclosed
US-20200056076-A1 IONIC POLYMERS AND THEIR USE AS WET-ADHESIVES AND COATINGS ACatechol, Inc. (US) 2020-02-20 US disclosed
US-20160246200-A1 PIGMENT DISPERSION AND TONER CANON KABUSHIKI KAISHA (JP) 2016-08-25 US disclosed
EP-2753982-B1 TONER CANON KK (JP) 2016-03-23 EP disclosed
US-9223240-B2 Toner CANON KABUSHIKI KAISHA (JP) 2015-12-29 US disclosed
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140205943-A1 TONER CANON KABUSHIKI KAISHA (JP) 2014-07-24 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
US-20130065174-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 US disclosed
WO-2013035885-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696698-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 GLRA3 28/4885GLRB 156/4885CYP3A4 3345/4885
US-11453790-B2 Photo-cleavable primer compositions and methods of use SP1, GPER1, ESR1 GLRA3 129/4885GLRB 367/4885CYP3A4 1274/4885
US-11352512-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 GLRA3 28/4885GLRB 156/4885CYP3A4 3345/4885
US-20200347247-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 GLRA3 28/4885GLRB 156/4885CYP3A4 3345/4885
US-20200347248-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, ESR1 GLRA3 129/4885GLRB 367/4885CYP3A4 1274/4885
US-20230112086-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, ESR1 GLRA3 129/4885GLRB 367/4885CYP3A4 1274/4885
US-11739223-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 GLRA3 28/4885GLRB 156/4885CYP3A4 3345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.