SCHEMBL6466602

SCHEMBL6466602

CC(C)(C)c1cc(C(C)(C)C)c(C(=O)O)c(C(C)(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.57
GLRB P48167 1/20 0.57
RXRB P28702 6/20 0.46
RXRA P19793 5/20 0.46
RXRG P48443 2/20 0.46
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
SRD5A2 P31213 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 1/20 0.39
HSP90AA1 P07900 1/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 1/20 0.39
NR5A2 O00482 1/20 0.38
NR5A1 Q13285 1/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
ALOX15 P16050 2/20 0.38
CYP1A2 P05177 2/20 0.38
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28419884 0.98 GLRA3 (0.55) GLRA3GLRBRXRBRXRARXRG
SCHEMBL16147679 0.88 GLRA3 (0.55) GLRA3GLRBRXRBRXRARXRG
SCHEMBL6130117 0.84 GLRA3 (0.59) GLRA3GLRBRXRBRXRARXRG
SCHEMBL5696383 0.82 GLRA3 (0.63) GLRA3GLRBGABRA1GABRB2SMN1; SMN2
SCHEMBL27417339 0.82 GLRA3 (0.57) GLRA3GLRBRXRBRXRASMN1; SMN2
SCHEMBL14825538 0.82 GLRA3 (0.42) GLRA3GLRBRXRBRXRARXRG
SCHEMBL5267910 0.82 GLRA3 (0.44) GLRA3GLRBRXRBRXRARXRG
SCHEMBL11606874 0.80 GLRA3 (0.61) GLRA3GLRBGABRA1GABRB2SMN1; SMN2
SCHEMBL14988234 0.80 GLRA3 (0.41) GLRA3GLRBRXRBRXRARXRG
SCHEMBL501930 0.79 RXRB (0.50) GLRA3GLRBRXRBRXRARXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107056587-B Method for synthesizing L-menthol 福建青松股份有限公司 2020-06-05 CN claimed
US-6010975-A Catalyst composition for preparing 3-pentenoic ester from butadiene INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2000-01-04 US claimed
US-20230367214-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-16 US disclosed
US-20230367213-A1 MASK BLANK, RESIST PATTERN FORMING PROCESS AND CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-16 US disclosed
US-20230367213-A1 MASK BLANK, RESIST PATTERN FORMING PROCESS AND CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-16 US disclosed
US-20230367214-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-16 US disclosed
EP-4276534-A1 MASK BLANK, RESIST PATTERN FORMING PROCESS AND CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2023-11-15 EP disclosed
US-20230194986-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-22 US disclosed
US-20230194986-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-22 US disclosed
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
US-11548844-B2 Monomer, polymer, negative resist composition, photomask blank, and resist pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-10 US disclosed
US-9348227-B2 Chemically amplified resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-24 US disclosed
US-20150355544-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-12-10 US disclosed
US-20150355544-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-12-10 US disclosed
US-20050014954-A1 Pyrrole synthesis CIBA SPECIALTY CHEMICALS CORP. 2005-01-20 US disclosed
EP-1451179-A1 PYRROLE SYNTHESIS Ciba SC Holding AG (CH) 2004-09-01 EP disclosed
WO-2003044011-A1 PYRROLE SYNTHESIS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-6010975-A Catalyst composition for preparing 3-pentenoic ester from butadiene INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2000-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014954-A1 Pyrrole synthesis PNPO, PPOX, DHPS GLRA3 4802/4885GLRB 4716/4885RXRB 4326/4885
US-11548844-B2 Monomer, polymer, negative resist composition, photomask blank, and resist pattern forming process PARG, PCNA, PLK2 GLRA3 1268/4885GLRB 434/4885RXRB 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.