SCHEMBL14760975

SCHEMBL14760975

C=Cc1cccc(C(C)(C)C)c1CCl

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 1/20 0.38
CA2 P00918 1/20 0.36
ALDH1A1 P00352 2/20 0.35
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15524568 0.88 ALOX12 (0.37) ALOX12CA2ALDH1A1GABRA1GABRB2
SCHEMBL15524808 0.82 ALOX12 (0.38) ALOX12CA2ALDH1A1GABRA1GABRB2
SCHEMBL22804518 0.82 ALOX12 (0.38) ALOX12CA2ALDH1A1GABRA1GABRB2
SCHEMBL15523822 0.79 ALOX12 (0.36) ALOX12CA2GABRA1GABRB2
SCHEMBL8322402 0.78 ALOX12 (0.35) ALOX12CA2ALDH1A1GABRA1GABRB2
SCHEMBL5871097 0.76 ALOX12 (0.33) ALOX12CA2
SCHEMBL9413121 0.76 ALDH1A1 (0.39) CA2ALDH1A1TSHRTDP1
SCHEMBL27805 0.74 ALDH1A1 (0.50) ALOX12CA2ALDH1A1GABRA1GABRB2
SCHEMBL29801228 0.74 ALDH1A1 (0.50) ALOX12CA2ALDH1A1GABRA1GABRB2
SCHEMBL28052307 0.73 CA2 (0.33) ALOX12CA2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9618867-B2 Pigment dispersion and toner CANON KABUSHIKI KAISHA (JP) 2017-04-11 US disclosed
US-20160246200-A1 PIGMENT DISPERSION AND TONER CANON KABUSHIKI KAISHA (JP) 2016-08-25 US disclosed
EP-2753982-B1 TONER CANON KK (JP) 2016-03-23 EP disclosed
US-9223240-B2 Toner CANON KABUSHIKI KAISHA (JP) 2015-12-29 US disclosed
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140205943-A1 TONER CANON KABUSHIKI KAISHA (JP) 2014-07-24 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
US-20130065174-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 US disclosed
WO-2013035885-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 WO disclosed