SCHEMBL147615

SCHEMBL147615

[CH2][C](c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.56
CES1 P23141 6/20 0.56
TSHR P16473 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
BLM P54132 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
POLB P06746 1/20 0.50
PARP1 P09874 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
DAO P14920 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
ALDH1A1 P00352 1/20 0.47
AKT1 P31749 1/20 0.43
CA2 P00918 3/20 0.43
F2 P00734 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7542937 0.79 TDP1 (0.50) CES2CES1TSHRCYP3A4MAPT
SCHEMBL4133635 0.79
SCHEMBL7542933 0.79 TDP1 (0.50) CES2CES1TSHRCYP3A4MAPT
SCHEMBL6046218 0.77 TDP1 (0.56) CES2CES1TSHRCYP3A4MAPT
SCHEMBL717977 0.77 TDP1 (0.56) CES2CES1TSHRCYP3A4MAPT
SCHEMBL6401253 0.77 TDP1 (0.56) CES2CES1TSHRCYP3A4MAPT
SCHEMBL424294 0.76
SCHEMBL688558 0.76
Benzil SCHEMBL28225310 0.73 CES2 (0.88) CES2CES1TSHRCYP3A4MAPT
Benzil SCHEMBL8382614 0.73 CES2 (0.88) CES2CES1TSHRCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 US claimed
US-20190177469-A1 CURABLE RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2019-06-13 US claimed
US-11827796-B2 Curable resin composition for three-dimensional shaping and method of manufacturing three-dimensionally shaped product CANON KABUSHIKI KAISHA (JP) 2023-11-28 US disclosed
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 US disclosed
CN-112352017-B Aqueous resin composition and method for producing same DIC株式会社 2023-04-07 CN disclosed
WO-2021024894-A1 AQUEOUS RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DIC株式会社 2021-02-11 WO disclosed
CN-112352017-A Aqueous resin composition and method for producing same DIC株式会社 2021-02-09 CN disclosed
US-20190315981-A1 CURABLE RESIN COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND METHOD OF MANUFACTURING THREE-DIMENSIONALLY SHAPED PRODUCT CANON KABUSHIKI KAISHA (JP) 2019-10-17 US disclosed
US-20190177469-A1 CURABLE RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2019-06-13 US disclosed
US-20150025262-A1 BIS(ARYL)ACETAL COMPOUNDS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-01-22 US disclosed
US-8933239-B1 Bis(aryl)acetal compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-20120059119-A1 THERMOSETTING POLYIMIDE RESIN COMPOSITION, CURED PRODUCT, AND ADHESIVE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-03-08 US disclosed
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed
EP-1173438-A1 SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2002-01-23 EP disclosed
US-6255532-B1 REACTING PYRILIUM SALTS WITH PHOSPHINE; CONSTANT PRESSURE; ACID CATALYST BASF AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed
US-6252117-B1 NONCATALYTIC REACTION OF PYRILLIUM SALT WITH PHOSPHINE SUPPLIED DURING THE REACTION TO MAINTAIN A UNIFORM PHOSPHINE PARTIAL PRESSURE BASF AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed
WO-2000063208-A1 SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025262-A1 BIS(ARYL)ACETAL COMPOUNDS BOLA2; BOLA2B, TARS1, CBR1 CES2 1281/4885CES1 1604/4885TSHR 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.