Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGDS | O60760 | 5/20 | 0.36 |
| ▸ | MET | P08581 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | YES1 | P07947 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181871 | 1.00 | HPGD (0.42) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL14763267 | 0.91 | ALDH1A1 (0.35) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL14769653 | 0.91 | MET (0.36) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL14859826 | 0.91 | MET (0.36) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL12181858 | 0.91 | ALDH1A1 (0.35) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL534690 | 0.91 | ALDH1A1 (0.34) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL535446 | 0.91 | ALDH1A1 (0.34) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL534691 | 0.91 | ALDH1A1 (0.34) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL535447 | 0.91 | ALDH1A1 (0.34) | HPGDALDH1A1F2GLAKDM4E | |
| SCHEMBL14860037 | 0.89 | MET (0.39) | HPGDALDH1A1F2GLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | CYP51A1, DDT, CYP4X1 | HPGD 4473/4885ALDH1A1 264/4885F2 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.