Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706936 | 0.92 | LMNA (0.42) | TSHRLMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL10430878 | 0.85 | ALDH1A1 (0.48) | TSHRLMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL2141472 | 0.84 | HDAC1 (0.41) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL2925049 | 0.83 | TSHR (0.56) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL11652184 | 0.83 | LMNA (0.53) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL5712400 | 0.83 | LMNA (0.48) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL10417803 | 0.82 | LMNA (0.52) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL7701703 | 0.80 | TSHR (0.52) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL11837665 | 0.80 | GPR84 (0.38) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL9849076 | 0.80 | LMNA (0.60) | KMT2AMEN1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322988-B2 | Process for purifying a stream comprising 1,4-butanediol | JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) | 2019-06-18 | — | — | US | disclosed |
| EP-2753597-B1 | PROCESS FOR PURIFYING A STREAM COMPRISING 1,4-BUTANEDIOL | JOHNSON MATTHEY DAVY TECHNOLOGIES LTD (GB) | 2018-10-17 | — | — | EP | disclosed |
| US-20140350308-A1 | Process For Purifying a Stream Comprising 1,4-Butanediol | JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| WO-2013034881-A1 | PROCESS FOR PURIFYING A STREAM COMPRISING 1,4- BUTANEDIOL | DAVY PROCESS TECHNOLOGY LIMITED (GB) | 2013-03-14 | — | — | WO | disclosed |