Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215047 | 0.86 | CSNK2A1 (0.66) | CYP1A2CYP3A4TSHRNFKB1MEN1 | |
| SCHEMBL1031519 | 0.85 | ALDH1A1 (0.54) | TSHRMEN1LMNAKMT2ACSNK2A1 | |
| SCHEMBL10757057 | 0.85 | TRPA1 (0.57) | CYP1A2CYP3A4TSHRNFKB1PDE4A | |
| Hydrochloric Acid SCHEMBL11548357 | 0.84 | LMNA (0.71) | CYP1A2CYP3A4TSHRNFKB1MEN1 | |
| Hydrochloric Acid SCHEMBL3560581 | 0.84 | CSNK2A1 (0.67) | CYP1A2CYP3A4TSHRNFKB1MEN1 | |
| Hydrochloric Acid SCHEMBL5065617 | 0.84 | LMNA (0.53) | TSHRMEN1LMNAAPEX1KMT2A | |
| Hydrochloric Acid SCHEMBL3564338 | 0.83 | CSNK2A1 (0.62) | CYP1A2CYP3A4TSHRNFKB1MEN1 | |
| SCHEMBL5240461 | 0.82 | CSNK2A1 (0.51) | CYP1A2CYP3A4TSHRMEN1LMNA | |
| SCHEMBL23494891 | 0.81 | PDE4A (0.47) | CYP1A2CYP3A4TSHRNFKB1MEN1 | |
| SCHEMBL532205 | 0.81 | CNR1 (0.53) | CYP1A2CYP3A4TSHRNFKB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190085007-A1 | 4-methylcatechol Derivatives and Uses Thereof | Thanares GmbH (DE) | 2019-03-21 | — | — | US | claimed |
| US-20160347782-A1 | 4-methylcatechol Derivatives and Uses Thereof | Thanares GmbH (DE) | 2016-12-01 | — | — | US | claimed |
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | claimed |
| US-20190085007-A1 | 4-methylcatechol Derivatives and Uses Thereof | Thanares GmbH (DE) | 2019-03-21 | — | — | US | disclosed |
| US-20160347782-A1 | 4-methylcatechol Derivatives and Uses Thereof | Thanares GmbH (DE) | 2016-12-01 | — | — | US | disclosed |
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190085007-A1 | 4-methylcatechol Derivatives and Uses Thereof | ST3GAL3, GALE, DPP4 | CYP1A2 241/4885CYP3A4 27/4885TSHR 4840/4885 |
| US-20160347782-A1 | 4-methylcatechol Derivatives and Uses Thereof | ST3GAL3, GALE, DPP4 | CYP1A2 241/4885CYP3A4 27/4885TSHR 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.