Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29160849 | 0.78 | TP53 (0.49) | ALDH1A1MEN1KMT2ATP53PDE3B | |
| SCHEMBL24853337 | 0.78 | TP53 (0.49) | ALDH1A1MEN1KMT2ATP53PDE3B | |
| SCHEMBL7174583 | 0.77 | BRPF1 (0.52) | BRPF1CREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL14765191 | 0.77 | CREBBP (0.61) | BRPF1CREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL11654866 | 0.76 | PDE3B (0.47) | CREBBPALDH1A1PDE3BPDE3AMAOA | |
| SCHEMBL16053338 | 0.76 | BRPF1 (0.59) | BRPF1CREBBPMEN1KMT2ATP53 | |
| SCHEMBL2136049 | 0.76 | BRPF1 (0.59) | BRPF1CREBBPMEN1KMT2ACA2 | |
| SCHEMBL21606298 | 0.75 | MEN1 (0.60) | BRPF1CREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL30908507 | 0.75 | MEN1 (0.60) | BRPF1CREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL4848196 | 0.75 | CA2 (0.47) | ALDH1A1TP53PDE3BPDE3AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034755-A1 | TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |