Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.61 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908117 | 0.81 | ROS1 (0.54) | CREBBPBRPF1MEN1KMT2ACSNK1G1 | |
| SCHEMBL2136049 | 0.80 | BRPF1 (0.59) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL16053338 | 0.80 | BRPF1 (0.59) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL14764993 | 0.77 | BRPF1 (0.56) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL12597037 | 0.77 | CREBBP (0.66) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL10327064 | 0.76 | CREBBP (1.00) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL1101924 | 0.76 | CREBBP (1.00) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL7668762 | 0.76 | CREBBP (1.00) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL29893035 | 0.76 | MEN1 (0.64) | CREBBPBRPF1MEN1KMT2AGSK3B | |
| SCHEMBL27077382 | 0.76 | MEN1 (0.64) | CREBBPBRPF1MEN1KMT2AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034755-A1 | TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |