Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952691 | 0.83 | GABRA1 (0.44) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL173732 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1LMNAALDH1A1 | |
| SCHEMBL2170193 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL4415273 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL3261826 | 0.80 | IMPDH2 (0.37) | GABRA1GABRB2ALDH1A1HSD17B10 | |
| SCHEMBL18136 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL7702457 | 0.77 | GABRA1 (0.40) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL968136 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL2362269 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1KMT2AMAPT | |
| SCHEMBL4170461 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2AKR1B1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034777-A2 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | disclosed |