Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD5 | P21918 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769321 | 0.84 | LOXL2 (0.37) | TAAR1HTR2ALOXL2PNMT | |
| SCHEMBL13443566 | 0.83 | HRH3 (0.40) | TAAR1HTR2ALOXL2CCR5SNCA | |
| SCHEMBL27834140 | 0.82 | KDM4E (0.44) | TAAR1HTR2ASLC6A2SLC6A4SNCA | |
| Hydrochloric Acid SCHEMBL27804601 | 0.81 | CA1 (0.39) | TAAR1LOXL2CCR5SNCAMAPT | |
| SCHEMBL10264740 | 0.78 | CA2 (0.36) | TAAR1HTR2ASLC6A2SLC6A4CCR5 | |
| SCHEMBL27857434 | 0.78 | CA1 (0.33) | TAAR1HTR2ALOXL2CCR5SNCA | |
| SCHEMBL18501731 | 0.73 | HRH3 (0.42) | TAAR1SLC6A2SLC6A4CCR5SLC6A3 | |
| SCHEMBL3910128 | 0.72 | MPO (0.44) | TAAR1HTR2ALOXL2ALDH1A1 | |
| SCHEMBL28879858 | 0.72 | CYP2A6 (0.47) | TAAR1HTR2ACCR5KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL856646 | 0.71 | MPO (0.43) | TAAR1HTR2ALOXL2ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036869-A2 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-03-14 | — | — | WO | disclosed |