Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.50 |
| ▸ | TDP2 | O95551 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | DHODH | Q02127 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052720 | 0.83 | MAPT (0.51) | APAF1TDP2MAPTMEN1KMT2A | |
| SCHEMBL5821364 | 0.79 | APAF1 (0.65) | APAF1TDP2MAPTMEN1KMT2A | |
| SCHEMBL939989 | 0.79 | APAF1 (0.54) | APAF1TDP2MAPTMEN1KMT2A | |
| SCHEMBL8462690 | 0.78 | MAPT (0.47) | APAF1TDP2MAPTMEN1KMT2A | |
| SCHEMBL12127298 | 0.76 | DHODH (0.79) | APAF1TDP2MAPTMEN1KMT2A | |
| Lapachol SCHEMBL31492698 | 0.76 | DHODH (0.79) | APAF1TDP2MAPTMEN1KMT2A | |
| Lapachol SCHEMBL157255 | 0.76 | DHODH (0.79) | APAF1TDP2MAPTMEN1KMT2A | |
| SCHEMBL1520566 | 0.75 | APAF1 (0.65) | APAF1TDP2MAPTMEN1KMT2A | |
| Lapachol SCHEMBL18769814 | 0.75 | DHODH (0.77) | APAF1TDP2MAPTMEN1KMT2A | |
| Lapachol SCHEMBL3274147 | 0.75 | DHODH (0.77) | APAF1TDP2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036766-A1 | SMALL MOLECULE NAPHTHOQUINONE- AND PHTHALIMIDE-BASED LIPOCATIONS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-03-14 | — | — | WO | disclosed |