SCHEMBL14765776

SCHEMBL14765776

CCCCOc1ccc(C2CCC(COc3ccc(C4CCC(OCCCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 3/20 0.35
FFAR1 O14842 12/20 0.35
CRBN Q96SW2 1/20 0.35
PPARD Q03181 3/20 0.34
SCN9A Q15858 1/20 0.33
ACACB O00763 1/20 0.33
HCRTR2 O43614 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766027 0.97 GPR119 (0.37) GPR119FFAR1CRBNPPARDSCN9A
SCHEMBL14766181 0.97 GPR119 (0.37) GPR119FFAR1CRBNPPARDACACB
SCHEMBL14766666 0.95 FFAR1 (0.38) FFAR1CRBNPPARDSCN9AACACB
SCHEMBL14765903 0.94 FFAR1 (0.33) GPR119FFAR1CRBNPPARDACACB
SCHEMBL14766176 0.93 FFAR1 (0.32) GPR119FFAR1CRBNPPARDSCN9A
SCHEMBL14766962 0.92 FFAR1 (0.38) GPR119FFAR1PPARDSCN9AACACB
SCHEMBL14766694 0.92 FFAR1 (0.38) GPR119FFAR1CRBNPPARDACACB
SCHEMBL12735918 0.91 SCN9A (0.41) FFAR1CRBNPPARDSCN9AACACB
SCHEMBL14766687 0.91 FFAR1 (0.40) FFAR1PPARDSCN9A
SCHEMBL14765812 0.90 ALOX5AP (0.35) GPR119SCN9AACACBHCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed