SCHEMBL14766176

SCHEMBL14766176

C=CCCOc1ccc(C2CCC(COc3ccc(C4CCC(OCCCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.32
GPR119 Q8TDV5 3/20 0.32
ACACB O00763 3/20 0.32
SCN9A Q15858 2/20 0.32
CRBN Q96SW2 1/20 0.31
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765903 0.97 FFAR1 (0.33) FFAR1GPR119ACACBCRBNPPARD
SCHEMBL14767041 0.96 FFAR1 (0.34) FFAR1ACACBSCN9ACRBNPPARD
SCHEMBL14766432 0.94 FFAR1 (0.33) FFAR1GPR119ACACBSCN9APPARD
SCHEMBL14767094 0.93 FFAR1 (0.35) FFAR1ACACBCRBNPPARD
SCHEMBL14765776 0.93 GPR119 (0.35) FFAR1GPR119ACACBSCN9ACRBN
SCHEMBL14766703 0.92 FFAR1 (0.36) FFAR1SCN9APPARD
SCHEMBL14766808 0.92 SCN9A (0.33) ACACBSCN9A
SCHEMBL14765964 0.92 SCN9A (0.33) ACACBSCN9A
SCHEMBL14766027 0.90 GPR119 (0.37) FFAR1GPR119SCN9ACRBNPPARD
SCHEMBL14766181 0.90 GPR119 (0.37) FFAR1GPR119ACACBCRBNPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed