SCHEMBL14766181

SCHEMBL14766181

CCCCOc1ccc(C2CCC(COc3ccc(C4CCC(OCCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 4/20 0.37
FFAR1 O14842 11/20 0.35
ACACB O00763 1/20 0.35
CRBN Q96SW2 1/20 0.34
PPARD Q03181 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HCRTR2 O43614 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765776 0.97 GPR119 (0.35) GPR119FFAR1ACACBCRBNPPARD
SCHEMBL14766694 0.95 FFAR1 (0.38) GPR119FFAR1ACACBCRBNPPARD
SCHEMBL14766027 0.94 GPR119 (0.37) GPR119FFAR1CRBNPPARDHCRTR2
SCHEMBL14766666 0.92 FFAR1 (0.38) FFAR1ACACBCRBNPPARD
SCHEMBL14767056 0.91 FFAR1 (0.39) FFAR1PPARD
SCHEMBL14765903 0.91 FFAR1 (0.33) GPR119FFAR1ACACBCRBNPPARD
SCHEMBL14766159 0.91 ALOX5AP (0.34) GPR119HCRTR2
SCHEMBL14766761 0.91 ALOX5AP (0.34) GPR119HCRTR2
SCHEMBL14766176 0.90 FFAR1 (0.32) GPR119FFAR1ACACBCRBNPPARD
SCHEMBL12735918 0.90 SCN9A (0.41) FFAR1ACACBCRBNPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed