Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | FEN1 | P39748 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CPS1 | P31327 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765686 | 0.94 | FFAR4 (0.44) | LMNAFFAR4FFAR1ALOX5APFEN1 | |
| SCHEMBL12733958 | 0.91 | FFAR4 (0.39) | LMNAMAPTFFAR4FFAR1ALOX5AP | |
| SCHEMBL12716345 | 0.90 | ALOX5AP (0.40) | LMNAALOX5APFEN1SYKCYP11B1 | |
| SCHEMBL12716114 | 0.90 | FFAR4 (0.38) | FFAR4FFAR1ALOX5APFEN1 | |
| SCHEMBL12733955 | 0.89 | FFAR4 (0.40) | FFAR4FFAR1ALOX5APFEN1FPR2 | |
| SCHEMBL12823282 | 0.88 | FFAR1 (0.40) | LMNAHTTMAPTFFAR4FFAR1 | |
| SCHEMBL12822245 | 0.88 | LMNA (0.39) | LMNAHTTMAPTFFAR4FFAR1 | |
| SCHEMBL12718970 | 0.88 | NAAA (0.41) | LMNAHTTMAPTFFAR4ALOX5AP | |
| SCHEMBL12733950 | 0.88 | FFAR4 (0.38) | FFAR4FFAR1ALOX5APFEN1NPC1 | |
| SCHEMBL13586430 | 0.88 | FFAR1 (0.40) | FFAR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |