Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733958 | 0.94 | FFAR4 (0.39) | FFAR4FFAR1CAMKK1CAMKK2LMNA | |
| SCHEMBL14765799 | 0.94 | LMNA (0.41) | FFAR4FFAR1NPC1ALDH1A1LMNA | |
| SCHEMBL12716114 | 0.93 | FFAR4 (0.38) | FFAR4FFAR1CAMKK1CAMKK2PPARD | |
| SCHEMBL12733955 | 0.92 | FFAR4 (0.40) | FFAR4FFAR1CAMKK1CAMKK2PPARD | |
| SCHEMBL14765702 | 0.91 | FFAR4 (0.38) | FFAR4FFAR1CAMKK1CAMKK2PPARD | |
| SCHEMBL12733950 | 0.91 | FFAR4 (0.38) | FFAR4FFAR1CAMKK1CAMKK2PPARD | |
| SCHEMBL12733952 | 0.90 | FFAR4 (0.36) | FFAR4FFAR1CAMKK1CAMKK2PPARD | |
| SCHEMBL14765684 | 0.89 | FFAR4 (0.41) | FFAR4FFAR1CAMKK1CAMKK2PPARD | |
| SCHEMBL12716257 | 0.89 | PTGS2 (0.41) | FFAR4FFAR1CAMKK1CAMKK2LMNA | |
| SCHEMBL12733953 | 0.89 | FFAR4 (0.36) | FFAR4FFAR1CAMKK1CAMKK2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |