SCHEMBL14765867

SCHEMBL14765867

C=CCOc1ccc(-c2ccc(COc3ccc(-c4ccc(OCC)cc4)c(F)c3F)cc2)cc1F

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 8/20 0.44
PPARD Q03181 6/20 0.44
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
ERN1 O75460 1/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2D6 P10635 1/20 0.36
KMT2A Q03164 1/20 0.36
MGAM O43451 3/20 0.36
GAA P10253 3/20 0.36
SI P14410 3/20 0.36
MGAM2 Q2M2H8 3/20 0.36
BCHE P06276 1/20 0.36
GYS1 P13807 1/20 0.35
GSTP1 P09211 1/20 0.34
NAAA Q02083 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767073 0.92 LMNA (0.40) FFAR1PPARDPPARGPPARALMNA
SCHEMBL14766513 0.92 LMNA (0.40) FFAR1PPARDPPARGPPARALMNA
SCHEMBL14767076 0.92 FFAR1 (0.48) FFAR1PPARDPPARGPPARALMNA
SCHEMBL14767096 0.92 FFAR1 (0.45) FFAR1PPARDPPARGPPARAERN1
SCHEMBL14766680 0.90 FFAR1 (0.48) FFAR1PPARDPPARGPPARALMNA
SCHEMBL14766172 0.90 FFAR1 (0.49) FFAR1PPARDPPARGPPARAERN1
SCHEMBL14766499 0.90 FFAR1 (0.43) FFAR1PPARDPPARGPPARAERN1
SCHEMBL12736543 0.89 FFAR4 (0.41) FFAR1PPARDERN1LMNAMEN1
SCHEMBL14766359 0.88 FFAR1 (0.40) FFAR1PPARDPPARGPPARALMNA
SCHEMBL14766202 0.88 FFAR1 (0.42) FFAR1PPARDPPARGPPARALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed