SCHEMBL14766680

SCHEMBL14766680

C=CCOc1ccc(COc2ccc(-c3ccc(-c4ccc(OCC)cc4)c(F)c3F)cc2)cc1F

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.48
PPARD Q03181 9/20 0.48
PPARA Q07869 4/20 0.48
PPARG P37231 2/20 0.48
GYS1 P13807 3/20 0.40
LMNA P02545 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP2D6 P10635 1/20 0.38
KMT2A Q03164 1/20 0.38
MGAM O43451 3/20 0.38
GAA P10253 3/20 0.38
SI P14410 3/20 0.38
MGAM2 Q2M2H8 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767076 0.94 FFAR1 (0.48) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL14766423 0.91 LMNA (0.39) FFAR1PPARDPPARAPPARGLMNA
SCHEMBL12740540 0.91 FFAR1 (0.41) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL14765867 0.90 FFAR1 (0.44) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL14767096 0.90 FFAR1 (0.45) FFAR1PPARDPPARAPPARGLMNA
SCHEMBL14767279 0.90 FFAR1 (0.52) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL14766800 0.89 FFAR1 (0.46) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL14767073 0.89 LMNA (0.40) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL14766513 0.89 LMNA (0.40) FFAR1PPARDPPARAPPARGGYS1
SCHEMBL10302563 0.88 GYS1 (0.40) FFAR1PPARDPPARAPPARGGYS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed