Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SI | P14410 | 3/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767073 | 1.00 | LMNA (0.40) | LMNAALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL14765867 | 0.92 | FFAR1 (0.44) | LMNAALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL14766359 | 0.91 | FFAR1 (0.40) | LMNAALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL14767076 | 0.90 | FFAR1 (0.48) | LMNAALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL14767096 | 0.90 | FFAR1 (0.45) | LMNAALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL14766680 | 0.89 | FFAR1 (0.48) | LMNAALDH1A1MEN1CYP2D6KMT2A | |
| SCHEMBL14767064 | 0.88 | NQO1 (0.41) | LMNAALDH1A1CYP2D6NPC1MAPT | |
| SCHEMBL14766357 | 0.88 | NQO1 (0.41) | LMNAALDH1A1CYP2D6NPC1MAPT | |
| SCHEMBL14765879 | 0.88 | CNR2 (0.37) | LMNAALDH1A1CYP2D6GAANPC1 | |
| SCHEMBL14767195 | 0.88 | CNR2 (0.37) | LMNAALDH1A1CYP2D6GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |