SCHEMBL14765880

SCHEMBL14765880

C=CCCOc1ccc(C2CCC(OCc3ccc(C4CCC(OCC)CC4)c(F)c3F)CC2)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
HTR1A P08908 1/20 0.31
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766987 1.00 GABRA1 (0.31) GABRA1GABRB2HTR1ANAAA
SCHEMBL12740220 0.94 KDM4E (0.31) HTR1A
SCHEMBL12736618 0.94 KDM4E (0.31) HTR1A
SCHEMBL14766254 0.93 SCN9A (0.32) GABRA1GABRB2
SCHEMBL14766854 0.93 SCN9A (0.32) GABRA1GABRB2
SCHEMBL10302592 0.93
SCHEMBL14765673 0.92 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL14765876 0.90 NAAA (0.35) NAAA
SCHEMBL14766814 0.90 HTR2C (0.36) GABRA1GABRB2HTR1ANAAA
SCHEMBL14766062 0.90 HTR2C (0.36) GABRA1GABRB2HTR1ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed