Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766273 | 0.92 | NAAA (0.35) | NAAAGABRA1GABRB2S1PR1NR1H4 | |
| SCHEMBL14765737 | 0.91 | NAAA (0.43) | NAAAS1PR1NR1H4FFAR4KCNH2 | |
| SCHEMBL12735414 | 0.90 | HTR2C (0.34) | NAAAHTR2CHTR2BHTR2AKDM4E | |
| SCHEMBL14766742 | 0.88 | GABRA1 (0.35) | GABRA1GABRB2HTR2CHTR2BABCG2 | |
| SCHEMBL14765728 | 0.88 | GABRA1 (0.35) | GABRA1GABRB2HTR2CHTR2BABCG2 | |
| SCHEMBL14766088 | 0.88 | NAAA (0.41) | NAAAGABRA1GABRB2HTR2CHTR2B | |
| SCHEMBL14766583 | 0.88 | NAAA (0.37) | NAAAGABRA1GABRB2HTR2CHTR2B | |
| SCHEMBL14766107 | 0.87 | S1PR1 (0.37) | NAAAGABRA1GABRB2S1PR1FFAR4 | |
| SCHEMBL14765943 | 0.87 | S1PR1 (0.37) | NAAAGABRA1GABRB2S1PR1FFAR4 | |
| SCHEMBL14767031 | 0.86 | GABRA1 (0.35) | NAAAGABRA1GABRB2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |