Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766917 | 0.94 | RARA (0.42) | FFAR4FFAR1RARARARBALDH1A1 | |
| SCHEMBL14767306 | 0.94 | FFAR4 (0.46) | FFAR4FFAR1RARARARBMAPT | |
| SCHEMBL14766404 | 0.92 | FFAR1 (0.42) | FFAR4FFAR1RARARARBALDH1A1 | |
| SCHEMBL12738289 | 0.91 | MAPT (0.38) | FFAR4FFAR1MAPTMCL1S1PR1 | |
| SCHEMBL14766983 | 0.90 | FFAR4 (0.41) | FFAR4FFAR1PTGS2MAPTTHRB | |
| SCHEMBL14766724 | 0.90 | FFAR4 (0.47) | FFAR4FFAR1PTGS2MAPTTHRB | |
| SCHEMBL14766094 | 0.89 | FFAR1 (0.38) | FFAR4FFAR1MAPTTHRBALDH1A1 | |
| SCHEMBL14767006 | 0.89 | FFAR1 (0.38) | FFAR4FFAR1MAPTTHRBALDH1A1 | |
| SCHEMBL14766401 | 0.89 | FFAR4 (0.51) | FFAR4FFAR1PTGS2RARARARB | |
| SCHEMBL12738291 | 0.89 | FFAR1 (0.38) | FFAR4FFAR1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |