Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766404 | 0.96 | FFAR1 (0.42) | RARARARBMCL1S1PR1S1PR3 | |
| SCHEMBL14766525 | 0.94 | FFAR4 (0.44) | RARARARBMCL1S1PR1S1PR3 | |
| SCHEMBL14767281 | 0.94 | RARA (0.46) | RARARARBMCL1S1PR1S1PR3 | |
| SCHEMBL14766424 | 0.92 | RARA (0.48) | RARARARBMCL1S1PR1S1PR3 | |
| SCHEMBL12738289 | 0.91 | MAPT (0.38) | MCL1S1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL14766716 | 0.90 | RARA (0.46) | RARARARBMCL1S1PR1S1PR3 | |
| SCHEMBL14766797 | 0.90 | RARA (0.47) | RARARARBMCL1S1PR1S1PR3 | |
| SCHEMBL14766333 | 0.89 | RARB (0.39) | RARARARBMCL1PTPN11FFAR1 | |
| SCHEMBL14767304 | 0.89 | RARB (0.39) | RARARARBMCL1PTPN11FFAR1 | |
| SCHEMBL14766401 | 0.89 | FFAR4 (0.51) | RARARARBMCL1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |