Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10646606 | 0.95 | TP53 (0.50) | TP53LMNATSHRALDH1A1TDP1 | |
| SCHEMBL29465010 | 0.94 | — | — | |
| SCHEMBL29465011 | 0.94 | — | — | |
| Bromide SCHEMBL377224 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11848392 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 | |
| Hydrogen Sulfide SCHEMBL401752 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 | |
| SCHEMBL401751 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 | |
| Fluoride Ion SCHEMBL19923301 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 | |
| Iodide SCHEMBL11013517 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL196471 | 0.89 | TP53 (0.53) | TP53LMNATSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630744-B2 | Polishing compositions and methods of use thereof | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2026-05-19 | — | — | US | claimed |
| EP-4688987-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| EP-4626996-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2025-10-08 | — | — | EP | claimed |
| US-20250257286-A1 | CLEANING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. | 2025-08-14 | — | — | US | claimed |
| US-20250075051-A1 | PROCESS FOR RECYCLING CONTAMINATED POLYMERS | ARKEMA FRANCE (FR) | 2025-03-06 | — | — | US | claimed |
| EP-4457275-A1 | PROCESS FOR RECYCLING CONTAMINATED POLYMERS | ARKEMA FRANCE (FR) | 2024-11-06 | — | — | EP | claimed |
| US-20240327675-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. | 2024-10-03 | — | — | US | claimed |
| WO-2024206301-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2024-10-03 | — | — | WO | claimed |
| WO-2024118398-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2024-06-06 | — | — | WO | claimed |
| US-20240174892-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. | 2024-05-30 | — | — | US | claimed |
| US-4170670-A | FORMALDEHYDE DONOR, AMMONIUM HYDROXIDE, TETRAKISHYDROXYMETHYLPHOSPHONIUM HYDROXIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1979-10-09 | — | — | US | claimed |
| US-4123573-A | APPLYING PHOSPHORUS COMPOSITION, WHICH HAS BEEN PRETREATED WITH AQUEOUS CAUSTIC SOLUTION, AND CURING | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-10-31 | — | — | US | claimed |
| US-4071501-A | Water soluble adduct of hydroxymethyl phosphorous compound and ammonia or amine compound and method of preparation | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1978-01-31 | — | — | US | claimed |
| US-4045173-A | Textiles flame retarded with hydroxymethylphosphorus compounds in combination with poly(ethyleneureas) and poly(N-methylolethyleneureas) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-08-30 | — | — | US | claimed |
| US-4017462-A | SOLUBILIZING WITH HYDROXYMETHYLPHOSPHONIUM SALTS AND FORMALDEHYDE, REACTION WITH PHENOLS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | claimed |
| US-3999941-A | Process for the manufacture of polycondensation products containing phosphorus, the products and their use as flameproofing agents | CIBA-GEIGY AG (CH) | 1976-12-28 | — | — | US | claimed |
| US-3994971-A | FIREPROOFING TEXTILES | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | claimed |
| US-3936562-A | Fire retardant fabrics | UNITED MERCHANTS AND MANUFACTURERS, INC. (US) | 1976-02-03 | — | — | US | claimed |
| US-3932502-A | Process for the manufacture of phosphorus-containing condensation products, the products and their use as flameproofing agents | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | claimed |
| US-3931310-A | TETRAKIS(HYDROXYMETHYL) PHOSPHONIUM AND DICYANDIAMIDE, FIRE RETARDANT | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630744-B2 | Polishing compositions and methods of use thereof | ZAP70, PRKDC, PEAK1 | TP53 2757/4885LMNA 2876/4885TSHR 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.