Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12740252 | 0.94 | KDM4E (0.35) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL14766491 | 0.93 | SCN9A (0.36) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL14766403 | 0.91 | DRD4 (0.38) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL14766992 | 0.90 | SCN9A (0.35) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL10302702 | 0.90 | HTR6 (0.36) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL12740253 | 0.90 | KDM4E (0.37) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL12822728 | 0.90 | DRD4 (0.33) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL14766882 | 0.89 | PPARD (0.36) | NAAAHTR6GABRA1GABRB2ALOX5AP | |
| SCHEMBL14766829 | 0.89 | FFAR1 (0.36) | DRD4NAAASIGMAR1HTR6TMEM97 | |
| SCHEMBL12740343 | 0.89 | SIGMAR1 (0.39) | DRD4NAAASIGMAR1HTR6TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |