Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766426 | 0.97 | GABRA1 (0.33) | GABRA1GABRB2SCN9ACNR2TUBB1 | |
| SCHEMBL14767052 | 0.94 | TUBB1 (0.34) | GABRA1GABRB2TUBB1FFAR4 | |
| SCHEMBL14766922 | 0.94 | TUBB1 (0.35) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766803 | 0.92 | TUBB1 (0.39) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766705 | 0.92 | TUBB1 (0.34) | GABRA1GABRB2SCN9ATUBB1ALDH1A1 | |
| SCHEMBL14766883 | 0.90 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL14765901 | 0.90 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL14766782 | 0.89 | GABRA1 (0.35) | GABRA1GABRB2SCN9ACNR2SMN1; SMN2 | |
| SCHEMBL14765868 | 0.88 | SCN9A (0.31) | GABRA1GABRB2SCN9A | |
| SCHEMBL14765861 | 0.88 | GABRA1 (0.31) | GABRA1GABRB2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |