Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766705 | 0.97 | TUBB1 (0.34) | TUBB1SCN9AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766803 | 0.97 | TUBB1 (0.39) | TUBB1SCN9AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766426 | 0.95 | GABRA1 (0.33) | TUBB1SCN9AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766684 | 0.94 | GABRA1 (0.32) | TUBB1SCN9AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12739420 | 0.91 | TUBB1 (0.34) | TUBB1SCN9AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766508 | 0.91 | TUBB1 (0.42) | TUBB1NAAAHPGDFFAR1PPARG | |
| SCHEMBL14765846 | 0.89 | — | — | |
| SCHEMBL14766792 | 0.89 | — | — | |
| SCHEMBL12739423 | 0.88 | KDM4E (0.35) | TUBB1SCN9AALDH1A1SMN1; SMN2PRKCE | |
| SCHEMBL14767052 | 0.87 | TUBB1 (0.34) | TUBB1FFAR4NAAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |